BOB1, Mouse anti-Human, HRP, Clone: BOB1/2424, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP275753H
DescriptionBOB1 Monoclonal antibody specifically detects BOB1 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).
|Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin|
|PBS with No Preservative|
|Recombinant human BOB1 (POU2AF1) protein fragment (around aa 148-255) (exact sequence is proprietary)|
|Protein A or G purified|
|Western Blot,Immunohistochemistry,Immunohistochemistry (Paraffin)|
|B-cell-specific coactivator OBF-1, BOB-1, OBF-1, OBF1BOB1, OCAB, OCA-B, OCT-binding factor 1, POU class 2 associating factor 1, POU domain class 2, associating factor 1, POU domain class 2-associating factor 1, POU domain, class 2, associating factor 1|
|Store at 4°C in the dark.|
|BOB1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB1. Conversely, only some cases of classical Hodgkin lymphoma show BOB1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.|
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