Tocris™ BPIPP

Non-competitive GC inhibitor. Also AC inhibitor

Manufacturer: Tocris™ 3635/10

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Catalog No. 36-351-0R

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For Research Use Only


    Quantity 10mg
    Inhibitors BPIPP
    Purity >99
    Molecular Weight 450.28
    Product Type BPIPP

    Non-competitive guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor. Downregulates cAMP and cGMP synthesis, and suppresses cGMP accumulation in a variety of cell lines (IC50 = 3.4 - 11.2µM). Inhibits GC-stimulated Cl- transport in vitro and suppresses toxin-induced intestinal fluid accumulation in vivo.

    • Chemical Name: 5-(3-Bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione
    • Formula: C22H16BrN3O3
    • CAS Number: 325746-94-9
    • Solubility: Soluble to 2mM in DMSO
    • Purity: >99

  • Description & Specifications

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