BRD4 Rabbit anti-Human, Mouse, Unconjugated, Polyclonal, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Active Motif 39010
DescriptionBRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.
|70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8|
|BOS_7204; Brd4; BRD4-NUT FUSION; Brd5; bromodomain containing 4; bromodomain-containing 4; bromodomain-containing 5; Bromodomain-containing protein 4; CAP; chromosome-associated protein; fsh-like protein; HUNK1; HUNKI; Mcap; Mitotic chromosome-associated protein; Protein HUNK1; WI-11513|
|This BRD4 antibody was raised against a peptide within the C-terminal region of human BRD4.|
|Antigen affinity chromatography|
|ChIP assay, Immunohistochemistry, Western Blot|
|-20°C, Avoid Freeze/Thaw Cycles|
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