BRD7 Rabbit anti-Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA549379
DescriptionBRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase.
|KLH conjugated synthetic peptide between 387-418 amino acids from the Central region of human MOUSE Brd7.|
|Antigen Affinity Chromatography, Protein A|
|PBS with 0.09% sodium azide|
|Bromodomain-containing protein 7, 75 kDa bromodomain protein, Brd7, Bp75|
|-20° C, Avoid Freeze/Thaw Cycles|
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