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BRD7 Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549379

Catalog No. PA549379


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Description

Description

BRD7 acts both as coactivator and as corepressor. For example, it activates the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. In addition, it is required for TP53-mediated cell-cycle arrest in response to oncogene activation. BRD7 promotes acetylation of TP53 at Lys-382, and thereby promotes efficient recruitment of TP53 to target promoters, inhibiting cell cycle progression from G1 to S phase.
Specifications

Specifications

Brd7
Polyclonal
Unconjugated
Brd7
Liquid
BRD7
KLH conjugated synthetic peptide between 387-418 amino acids from the Central region of human MOUSE Brd7.
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Mouse
Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
O88665
Bromodomain-containing protein 7, 75 kDa bromodomain protein, Brd7, Bp75
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
26992
Documents
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