Invitrogen™ BRP44L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA584267

Catalog No. PIPA584267

Description

Immunogen sequence: ATNEVAQLIQ GGRLIKHEMT KTA.

BRP44L (brain protein 44-like protein), also known as HSPC040 or CGI-129, is a 109 amino acid mitochondrial protein belonging to the UPF0041 family. The gene that encodes BRP44L maps to human chromosome 6. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

Specifications

• Antigen: BRP44L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MPC1
• Gene Alias: 0610006G08Rik; 3830411I18Rik; apoptosis-regulating basic protein; Arbp; Brain protein 44-like protein; Brp44l; CGI-129; dJ68L15.3; HSPC040; HSPC040 protein; mitochondrial pyruvate carrier 1; Mpc1; MPYCD; PNAS-115
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51660
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y5U8
• Gene Symbols: MPC1
• Immunogen: Recombinant protein corresponding to Human MPC1. Recombinant protein control fragment (Product #RP-106663).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov