Invitrogen™ BRPF3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531848

Catalog No. PIPA531848

Description

Recommended positive controls: U87-MG. Predicted reactivity: Mouse (94%), Rat (94%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity (PubMed:16387653, PubMed:26620551, PubMed:26677226). Plays a role in DNA replication initiation by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby facilitating the activation of replication origins (PubMed:26620551). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:16387653). [UniProt].

Specifications

• Antigen: BRPF3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BRPF3
• Gene Alias: AI413466; AW493400; bromodomain and PHD finger containing 3; bromodomain and PHD finger containing, 3; bromodomain and PHD finger-containing protein 3; BRPF3; KIAA1286; mKIAA1286
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 27154
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9ULD4
• Gene Symbols: BRPF3
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 224 of Human BRPF3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG