Tocris™ BTT 3033

Selective inhibitor of integrin alpha2beta1

Manufacturer: Tocris™ 4724/10

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Catalog No. 47-241-0

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Disclaimers:

For Research Use Only


    Specifications

    Product Type BTT 3033
    Inhibitors BTT 3033
    Purity >98
    Molecular Weight 465.5
    Quantity 10mg

    Selective inhibitor of integrin α2β1 (EC50 = 130nM for α2β1 binding to collagen I). Binds to the α2I domain. Exhibits selectivity for α2β1 over integrins α3β1, α4β1, α5β1 and αv. Inhibits platelet aggregation to collagen I coated capillaries under flow. Also inhibits binding of α2-expressing CHO cells to collagen I under shear stress conditions.

    • Chemical Name: 1-(4-Fluorophenyl)-N-methyl-N-[4[[(phenylamino)carbonyl]amino]phenyl]-1H-pyrazole-4-sulfonamide
    • Formula: C23H20FN5O3S
    • CAS Number: 1259028-99-3
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

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