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  8. BX 795, Tocris Bioscience™

BX 795, Tocris Bioscience™

Catalog Number 431810
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
702675-74-9
C23H26IN7O2S
591.47
MFCD12546134
VAVXGGRQQJZYBL-UHFFFAOYSA-N
n-3-5-iodo-4-3-2-thienylcarbonyl amino propyl amino-2-pyrimidinyl amino phenyl-1-pyrrolidinecarboxamide, n-3-5-iodo-4-3-thiophene-2-carbonylamino propylamino pyrimidin-2-yl amino phenyl pyrrolidine-1-carboxamide, n-3-4-3-thiophene-2-carbonylamino propylamino-5-iodopyrimidin-2-ylamino phenyl pyrrolidine-1-carboxamide, n-3-5-iodo-4-3-thiophene-2-carboxamido propylamino pyrimidin-2-ylamino phenyl pyrrolidine-1-carboxamide, n-3-5-iodo-4-3-thiophen-2-ylcarbonyl amino propyl amino pyrimidin-2-yl amino phenyl pyrrolidine-1-carboxamide, n-3-5-iodo-4-3-thiophen-2-ylformamido propyl amino pyrimidin-2-yl amino phenyl pyrrolidine-1-carboxamide, bx7, d0rg0z, n-3-5-iodo-4-3-thiophene-2-carboxamido propyl amino pyrimidin-2-yl amino phenyl pyrrolidine-1-carboxamide, n-3-4-2-2-formamidothiophen-3-yl propanamido-5-iodopyrimidin-2-ylamino phenyl pyrrolidine-1-carboxamide
10077147
N-(3-{[5-iodo-4-({3-[(thiophen-2-yl)formamido]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide
IC1=CN=C(NC2=CC(NC(=O)N3CCCC3)=CC=C2)N=C1NCCCNC(=O)C1=CC=CS1
This item is not returnable. View return policy
702675-74-9
C23H26IN7O2S
591.47
MFCD12546134
VAVXGGRQQJZYBL-UHFFFAOYSA-N
n-3-5-iodo-4-3-2-thienylcarbonyl amino propyl amino-2-pyrimidinyl amino phenyl-1-pyrrolidinecarboxamide, n-3-5-iodo-4-3-thiophene-2-carbonylamino propylamino pyrimidin-2-yl amino phenyl pyrrolidine-1-carboxamide, n-3-4-3-thiophene-2-carbonylamino propylamino-5-iodopyrimidin-2-ylamino phenyl pyrrolidine-1-carboxamide, n-3-5-iodo-4-3-thiophene-2-carboxamido propylamino pyrimidin-2-ylamino phenyl pyrrolidine-1-carboxamide, n-3-5-iodo-4-3-thiophen-2-ylcarbonyl amino propyl amino pyrimidin-2-yl amino phenyl pyrrolidine-1-carboxamide, n-3-5-iodo-4-3-thiophen-2-ylformamido propyl amino pyrimidin-2-yl amino phenyl pyrrolidine-1-carboxamide, bx7, d0rg0z, n-3-5-iodo-4-3-thiophene-2-carboxamido propyl amino pyrimidin-2-yl amino phenyl pyrrolidine-1-carboxamide, n-3-4-2-2-formamidothiophen-3-yl propanamido-5-iodopyrimidin-2-ylamino phenyl pyrrolidine-1-carboxamide
10077147
N-(3-{[5-iodo-4-({3-[(thiophen-2-yl)formamido]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide
IC1=CN=C(NC2=CC(NC(=O)N3CCCC3)=CC=C2)N=C1NCCCNC(=O)C1=CC=CS1

Description

PDPK1 (PDK1) inhibitor

Inhibitor of 3-phosphoinositide-dependent kinase 1 (PDPK1). Inhibits Akt phosphorylation at Thr308 in PC3 cells; also inhibits anchorage-independent growth of PC3 and MDA-MB-468 cells. Exhibits activity at other kinases, including TANK-binding kinase 1 (TBK1), Aurora B and IκB kinase ε (IKKε). Also enhances lentiviral transduction of natural killer (NK) cells by around 3.8-fold.
Quantity 10 mg
Formula Weight 591.47
Percent Purity >98%
Chemical Name or Material BX 795

Safety and Handling

Recommended Storage Store at -20°C
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