c-Myb Mouse anti-Human, Alexa Fluor 532, Clone: MYB286, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234690AF532
Descriptionc-Myb Monoclonal antibody specifically detects c-Myb in Human samples. It is validated for Western Blot,Flow Cytometry,ELISA,Immunocytochemistry,Immunofluorescence.
|Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence|
|c-myb, Cmyb, c-myb protein (140 AA), c-myb_CDS, c-myb10A_CDS, c-myb13A_CDS, c-myb14A_CDS, c-myb8B_CDS, efg, Proto-oncogene c-Myb, transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog, v-myb myeloblastosis viral oncogene homolog (avian)|
|Store at 4°C in the dark.|
|The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.|
|ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot|
|Alexa Fluor™ 532|
|50 mM sodium borate with 0.05% sodium azide|
|A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH|
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