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c-Myb Antibody (MYB286), Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2328370.02MG
Description
c-Myb Monoclonal specifically detects c-Myb in Human samples. It is validated for ELISA.Specifications
c-Myb | |
Monoclonal | |
Unconjugated | |
PBS with 0.05% BSA. with 0.05% Sodium Azide | |
c-myb, Cmyb, c-myb protein (140 AA), c-myb_CDS, c-myb10A_CDS, c-myb13A_CDS, c-myb14A_CDS, c-myb8B_CDS, efg, Proto-oncogene c-Myb, transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog, v-myb myeloblastosis viral oncogene homolog (avian) | |
Mouse | |
75 kDa | |
0.02 mg | |
Cancer, Phospho Specific | |
4602 | |
Human | |
Purified |
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation | |
MYB286 | |
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate | |
P10242 | |
MYB | |
A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH | |
Protein A purified | |
RUO | |
Primary | |
The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate. | |
Store at 4C. | |
IgG1 κ |
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