c-Myc Mouse anti-Human, Primate, Mouse, Alexa Fluor 532, Clone: MYC699, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234692AF532
Descriptionc-Myc Monoclonal antibody specifically detects c-Myc in Human,Primate,Mouse samples. It is validated for Flow Cytometry,Immunocytochemistry,Immunofluorescence.
|Flow Cytometry, Immunocytochemistry/Immunofluorescence|
|avian myelocytomatosis viral oncogene homolog, BHLHE39, bHLHe39MRTL, Class E basic helix-loop-helix protein 39, c-Myc, MYC, myc proto-oncogene protein, MYCC, myc-related translation/localization regulatory factor, Proto-oncogene c-Myc, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog (avian)|
|Store at 4°C in the dark.|
|The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence|
|Alexa Fluor™ 532|
|50 mM sodium borate with 0.05% sodium azide|
|A synthetic peptide, corresponding to aa 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQL-RNSCA) from C-terminus of human c-myc, coupled to KLH|
|Human, Mouse, Primate|
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