Invitrogen™ C15orf23 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559828

Catalog No. PIPA559828

Description

Immunogen sequence: TVYSLQPPSA LSGGQPADTQ TRATSKSLLP VRSKEVDVSK QLHSGGPEND VTKITKLRRE NGQMKATDTA TRRNVRKGYK PLSKQ Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 64%.

C15orf23 is an essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. It promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.

Specifications

• Antigen: C15orf23
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KNSTRN
• Gene Alias: 1700025D04Rik; C10H15orf23; C15orf23; D2Ertd750e; HSD11; Kinastrin; kinetochore localized astrin (SPAG5) binding protein; kinetochore localized astrin/SPAG5 binding protein; kinetochore-localized astrin/SPAG5 binding; kinetochore-localized astrin/SPAG5 binding protein; kinetochore-localized astrin/SPAG5-binding protein; kinetochore-localized astrin-binding protein; Knstrn; putative TRAF4-associated factor 1; SKAP; small kinetochore associated protein; small kinetochore-associated protein; small kinetochore-associated protein, kinetochore-localized astrin-binding protein, TRAF4 associated factor 1; TRAF4 associated factor 1; TRAF4 associated factor 1 homolog; TRAF4AF1; TRAF4-associated factor 1; Unknown (protein for MGC:134039)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 90417
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y448
• Gene Symbols: KNSTRN
• Immunogen: Recombinant protein corresponding to Human C15orf23. Recombinant protein control fragment (Product #RP-98059).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG