Invitrogen™ C19orf10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561304

Catalog No. PIPA561304

Description

Immunogen sequence: YLYFTQFKAE VRGAEIEYAM AYSKAAFERE SDVPLKTEEF EVTKTAVAHR PGAFKAELSK LVIVAKASRT EL Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 89%.

The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. IL-25 (also called SF20/IL-25) is a secreted bone marrow stroma-derived growth factor cytokine that is derived from Th2 T-cells. IL-25 belongs to the IL-17 cytokine family and is capable of amplifying allergic type inflammatory responses by its actions on other cell types. IL-25 binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation. Infusion of mice with IL-25 induces IL-4, IL-5, and IL-13 gene expression. IL-25 induced mice also develop epithelial cell hyperplasia, increased mucus secretion, and airway hyperreactivity, suggesting that IL-25 may be an important mediator of allergic disease via production of IL-4, IL-5, IL-13 and eotaxin.

Specifications

• Antigen: C19orf10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYDGF
• Gene Alias: C19orf10; CS010; D17Wsu104e; EUROIMAGE1875335; IL 25; IL 27; Il25; IL27; IL27w; interleukin 25; interleukin 27 working designation; Interleukin25; interleukin-25; LOC501282; Ly6elg; Mydgf; myeloid derived growth factor; myeloid-derived growth factor; R33729 1; R33729_1; R337291; SF20; similar to lymphocyte antigen 6 complex, locus E ligand; stromal cell-derived growth factor SF20; UPF0556 protein C19orf10; UPF0556 protein C19orf10 homolog
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56005
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q969H8
• Gene Symbols: MYDGF
• Immunogen: Recombinant protein corresponding to Human C19orf10. Recombinant protein control fragment (Product #RP-98885).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov