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C2 Mouse anti-Human, Clone: OTI12G10, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF807188

Catalog No. 50-166-8152


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Component C2 is a serum glycoprotein that functions aspart of the classical pathway of the complement system. ActivatedC1 cleaves C2 into C2a and C2b. The serine proteinase C2a thencombines with complement factor 4b to create the C3 or C5convertase. Deficiency of C2 has been reported to associated withcertain autoimmune diseases and SNPs in this gene have beenassociated with altered susceptibility to age-related maculardegeneration. This gene localizes within the class III region ofthe MHC on the short arm of chromosome 6. Alternative splicingresults in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publicationsbut their full-length sequence has not been determined.
Specifications

Specifications

C2
Monoclonal
Unconjugated
C2
Lyophilized
C2
Human recombit protein fragment corresponding to amino acids 469-752 of human C2 produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
OTI12G10
PBS with 8% trehalose and no preservative; pH 7.3
P06681
ARMD14, CO2
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
717
SDS
Documents
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