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C2b Rabbit anti-Human, Polyclonal, Bioss Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  BiossSupplier Diversity Partner BS15142R

Catalog No. 50-198-3494


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Description

Description

Component C2 is a serum glycoprotein that functions aspart of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
Specifications

Specifications

C2b
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
C2
Liquid
Rabbit
IgG
100 μL
-20°C
Primary
717
C2
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
P06681
ARMD14; C2; C3/C5 convertase; classical-complement pathway C3/C5 convertase; CO2; Complement C2; Complement C2a fragment; Complement C2b fragment; complement component 2; complement component 2 (within H-2S); complement component C2; complement factor C2; DADB-122G4.1; MHC complement component C2
KLH conjugated synthetic peptide derived from human Complement C2b fragment.
Protein A
RUO
Antibody
Polyclonal
Human
SDS
Documents
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