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Tocris™ C34

TLR4 inhibitor

Manufacturer:  Tocris™ 5373/10

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Catalog No. 53-731-0


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For Research Use Only


Specifications

Description

TLR4 inhibitor; attenuates TLR4 signaling in enterocytes and macrophages in vitro, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis (NEC). Also suppresses LPS signaling in human ileum displaying NEC ex-vivo. Displays no significant effects on signaling via TLR2 or TLR9.
  • Chemical Name: 1-Methylethyl 2-(acetylamino)-2-deoxy-α-D-glucopyranoside 3,4,6-triacetate
  • Formula: C17H27NO9
  • CAS Number: 40592-88-9
  • Solubility: Soluble to 50mM in water and to 100mM in DMSO
Description & Specifications

Specifications

C34
C34
389.4
10mg
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