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C4 alpha chain/C4b/C4d Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 222331AP

Catalog No. 50-173-3787


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Description

Description

This antibody raised against 1017-1336aa of human C4-A protein can recognize C4 precursor, C4 alpha chain, C4b, and C4d.

This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.
Specifications

Specifications

C4 alpha chain/C4b/C4d
0.25 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P0C0L4
Acidic complement C4, C4, C4A, C4A2, C4A3, C4A4, C4A6, C4S, CO4, Complement C4 A, CPAMD2, RG
Rabbit
IgG
150 μL
-20°C
Primary
720
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
C4A
Liquid
C4A
C4 alpha chain/C4b/C4d Fusion Protein Ag17583
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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