Invitrogen™ C9orf72 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109471

Catalog No. PIPA5109471

Description

Immunogen sequence: SPAVAKTEIA LSGKSPLLAA TFAYWDNILG PRVRHIWAPK TEQVLLSDGE ITFLANHTLN GEILRNAESG AIDVKFFVLS EKGVIIVSLI FDGNWNGDRS TYGLSIILPQ TELSFYLPLH RVCVDRLTHI IRKGRIWMHK ERQENVQKII LEGTERMEDQ GQSIIPMLTG EVIPVMELLS SMKSHSVPEE ID.

C9orf72 may play a role in endosomal trafficking and autophagy. It is known to interact with HNRNPA1, HNRNPA2B1, UBQLN2, and small Rab GTPSases. C9orf72 localizes in the nucleus, cytoplasm, endosome, lysosome, and autophagosome. Mutations in this gene can result in frontotemporal dementia and/or amyotrophic lateral sclerosis.

Specifications

• Antigen: C9orf72
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C9orf72
• Gene Alias: 3110043O21Rik; AI840585; ALSFTD; C9orf72; chromosome 9 open reading frame 72; FTDALS; FTDALS1; Guanine nucleotide exchange C9orf72; Guanine nucleotide exchange C9orf72 homolog; protein C9orf72; protein C9orf72 homolog; RGD1359108; RIKEN cDNA 3110043O21 gene; similar to RIKEN cDNA 3110043O21
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 203228, 313155, 73205
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.38 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q66HC3, Q96LT7
• Gene Symbols: C9orf72, RGD1359108
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 9-200 of human C9orf72 (NP_0012429831).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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