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CACNB4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 177701AP

Catalog No. 50-173-1781


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Description

Description

This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy and juvenile myoclonic epilepsy. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

CACNB4
0.16 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
D4A055, O00305, Q8R0S4
CAB4, CACNB4, CACNLB4, EA5, EJM
Rabbit
IgG
150 μL
-20°C
Primary
12298, 58942, 785
Western Blot
Unconjugated
CACNB4
Liquid
Cacnb4
CACNB4 Fusion Protein Ag12178
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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