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CACNG1 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 183891AP

Catalog No. 50-173-2137


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Description

Description

Voltage-dependent calcium channels are essential for the release of neurotransmitters. L-type (long lasting current) voltage-dependent calcium channels are composed of four subunits: an alpha1 subunit, a beta subunit, a gamma subunit and an alpha2 delta subunit. The beta subunit is encoded by four genes, designated beta1-beta4, all of which contribute to the diversity of calcium currents and are involved in membrane trafficking of the alpha1 subunit. L-type Ca ++ CP gamma1, also known as CACNLG or CACNG1, is a 222 amino acid multi-pass membrane protein belonging to the PMP-22/EMP/MP20 family. Expressed in skeletal muscle, L-type Ca ++ CP gamma1 is a subunit of the dihydropyridine (DHP) sensitive calcium channel and may play a role in excitation-contraction coupling. L-type Ca++ CP gamma1 is considered a novel marker for maligt hyperthermia susceptibility (MHS), an autosomal domit disorder of skeletal muscle which manifests as a life-threatening hypermetabolic crisis triggered by commonly used inhalation anaesthetics and depolarizing muscle relaxants.
Specifications

Specifications

CACNG1
0.25 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q06432
CACNG1, CACNLG
Rabbit
IgG
150 μL
-20°C
Primary
786
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Unconjugated
CACNG1
Liquid
CACNG1
CACNG1 Fusion Protein Ag12918
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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