CAD Monoclonal Antibody (OTI1A7), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA812727

Catalog No. 50-168-4668

Description

The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.

Specifications

• Antigen: CAD
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P27708
• Gene Symbols: CAD
• Immunogen: Human recombit protein fragment corresponding to amino acids 1918-2225 of human CAD produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1A7
• Conjugate: Unconjugated
• Gene: CAD
• Gene Alias: CDG1Z, EIEE50, GATD4
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 790
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid