MilliporeSigma™ Calbiochem™ 5′-Deoxy-5′-methylthioadenosine
Inhibits protein carboxymethyltransferase, induces apoptosis in leukemia U937 cells.
Manufacturer: MilliporeSigma™ 26058550MG
EMD Millipore Calbiochem™ 5′-Deoxy-5′-methylthioadenosine also inhibits FGF-2 receptor tyrosine kinase activity.
- Cell-permeable, reversible, ATP-competitive naturally-occurring co-product of polyamine biosynthesis that acts as an endogenous substrate of methylthioadenosine phosphorylase (MTAP)
- Inhibits proliferation of human astrocytes, glioma cells
- Assay: ≥99% by HPLC
- CAS: 2457-80-9
- Molecular Formula: C11H15N5O3S
- Color: White
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