MilliporeSigma™ Calbiochem™ A77 1726
Blocks TNF-dependent NF-κB activation gene expression, inhibits activity of dihydroorotate dehydrogenase.
Manufacturer: MilliporeSigma™ 1001285MG
- Cell-permeable, reversible, substrate competitive inhibitor that inhibits IL-2-induced tyrosine phosphorylation of JAK1 JAK3
- Reported to reduce IFN-γ-induced expression of iNOS in L929 fibroblasts
- Inhibits IL-1β-induced activation of COX-2 PGE2 synthesis (IC50 = 130nM) in A549 cells
- Assay: ≥97% by HPLC
- CAS: 108605-62-5
- Molecular Formula: C12H9F3N2O2
- Color: White
|2°C to 8°C|
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