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MilliporeSigma™ Calbiochem™ Adenosine A2B Receptor Antagonist I, MRS 1754

A p-cyanoanilide xanthine derivative that acts as a highly selective, high affinity antagonist of adenosine A2B receptor (A2B R;

Manufacturer:  MilliporeSigma™ 11915110MG

Catalog No. 11-915-110MG


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Description

Description

A p-cyanoanilide xanthine derivative that acts as a highly selective, high affinity antagonist of adenosine A2B receptor (A2BR; Ki = 1.97nM for human A2BR). Does not significantly affect other adenosine receptors (Ki = 403 nM, 503 nM, and 570nM for human A1R, A2AR, and A3R, respectively). Exhibits some antagonist action on rat A1R (Ki = 16.8nM). Shown to abolish the cardioprotective effects of NECA (Cat. No. 119140).
Specifications

Specifications

99% by HPLC
Protect from Light
Adenosine A2B Receptor
486.5g/mol
White solid
10mg
C26H26N6O4
DMSO
Documents
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