MilliporeSigma Calbiochem Adenosine A2B Receptor Antagonist I, MRS 1754
A p-cyanoanilide xanthine derivative that acts as a highly selective, high affinity antagonist of adenosine A2B receptor (A2B R;
Manufacturer: MilliporeSigma 11915110MG
DescriptionA p-cyanoanilide xanthine derivative that acts as a highly selective, high affinity antagonist of adenosine A2B receptor (A2BR; Ki = 1.97nM for human A2BR). Does not significantly affect other adenosine receptors (Ki = 403 nM, 503 nM, and 570nM for human A1R, A2AR, and A3R, respectively). Exhibits some antagonist action on rat A1R (Ki = 16.8nM). Shown to abolish the cardioprotective effects of NECA (Cat. No. 119140).
|99% by HPLC|
|Protect from Light|
|Adenosine A2B Receptor|
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