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EMD Millipore Calbiochem™ Aprotinin, Bovine, Recombinant, Nicotiana sp., Animal-Free Available on GSA/VA Contract for Federal Government customers only.

Aprotinin, Bovine, Recombinant, Nicotiana sp, Animal-Free - CAS 9087-70-1, is a heat and acid-stable competitive, reversible inhibitor of serine proteases.

Manufacturer:  EMD Millipore 6163711MG

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Catalog No. 61-637-11MG


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Specifications

Description

Recombinant, bovine aprotinin supplied without animal-derived components. Aprotinin is a competitive, reversible inhibitor of proteolytic and esterolytic activity. A relatively heat- and acid-stable serine protease inhibitor. Forms a tight complex, blocking the active site of the enzyme. Effective at concentrations equimolar with protease. Inhibits several proteases, including coagulation factors in the prephase of blood clotting, tissue and leukocytic proteinases, chymotrypsin, trypsin (Kd = 5 x 10-14 M), plasmin (Kd = 2.3 x 10-10 M), and kallikrein (Kd = 1 x 10-7 M). Proteases not inhibited by aprotinin include Factor Xa, thrombin, pepsin, papain, and carboxypeptidases A and B. Useful for protein purification and for extending the life of cells in culture by preventing proteolytic damage.
Description & Specifications

Specifications

In 0.9% NaCl. Contains no animal-derived components.
Clear, colorless to amber liquid
chymotrypsin
C284H432N84O79S7
95% by SDS-PAGE
1mg
9087-70-1
6512g/mol
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