Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

EMD Millipore Calbiochem™ Bafilomycin A1, Streptomyces griseus Available on GSA/VA Contract for Federal Government customers only.

Bafilomycin A1, CAS 88899-55-2, acts as a highly potent and specific inhibitor of vacuolar-type H+-ATPase (Ki = 500 pM). Blocks the fusion of autophagosome with lysosome.

Manufacturer:  EMD Millipore 1960001SET

 View more versions of this product

Catalog No. 19-600-01SET


  Check Availability
Add to cart

Specifications

Description

A macrolide antibiotic that acts as a specific inhibitor of vacuolar-type H+-ATPase (V-type; Ki = 500 pM). A valuable tool for distinguishing among different types of ATPases. Blocks lysosomal cholesterol trafficking in macrophages and is known to interfere with pH regulation in brain cells. Exhibits cytotoxic effects on a number of cell lines in a cell viability assay. Reported to selectively inhibit β-secretase, an enzyme involved in the processing of amyloid precursor protein (APP). The InSolution™ format with a purity of ≥97% by HPLC in 90% DMSO is also available (Cat. No. 508409).
Description & Specifications

Specifications

90% by HPLC
Protect from Light
vacuolar type H+ ATPase
C35H58O9
DMSO or EtOH
White solid
1 set
88899-55-2
622.8g/mol
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit