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MilliporeSigma™ Calbiochem™ Cyclophilin A, Human, Recombinant, E. coli

Recombiant, human cyclophilin A expressed in E.

Manufacturer:  MilliporeSigma™ 239777100UG

Catalog No. 23-977-7100UG

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Recombiant, human cyclophilin A expressed in E. coli . An ubiquitous enzyme that catalyzes the cis-trans- isomerization of X-Pro peptide bonds. Binds to proteins and acts as a chaperone in protein folding. Incorporates into HIV-1 virons and is believed to be essential for viral infectivity. Cyclophilin binds to the immunosuppressant Cyclosporin A (Cat. No. 239835). This complex then binds calcineurin (PP2B) and inhibits its phosphatase activity.


In 20 mM Tris-HCl, pH 7.8.
Catalyzes the cis-trans-isomerization of X-Pro peptide bonds
90% by SDS-PAGE
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