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MilliporeSigma™ Calbiochem™ Minocycline, Hydrochloride

Semi-synthetic tetracycline derivative effective against tetracycline-resistant staphylococci.

Manufacturer:  MilliporeSigma™ 47584350MG

Catalog No. 47-584-350MG


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Description

Description

Semi-synthetic tetracycline derivative effective against tetracycline-resistant staphylococci. A matrix metalloproteinase (MMP) inhibitor shown to inhibit tumor-induced angiogenesis. Inhibits stromelysin (MMP-3; IC50 = 290µM) but does not inhibit other MMPs such as fibroblast collagenase or gelatinase. Potently inhibits PARP-1 (K i = 13.4nM) in a NAD + - competitive manner. Exhibits anti-inflammatory effects and suppresses T cell proliferation.
Specifications

Specifications

98% by TLC
50mg
13614-98-7
493.9g/mol
Dark yellow solid
Metalloproteinase (MMP)
C23H27N3O7·HCl
H2O
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