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MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor X, Methysticin

Methysticin has been identified from kava to have potent NF-κB inhibitory activity and minimum toxicity

Manufacturer:  MilliporeSigma™ 4804585MG

Catalog No. 48-045-85MG


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Description

Description

Methysticin has been identified from kava to have potent NF-κB inhibitory activity and minimum toxicity. It is shown to inhibit NF-κB (IC50 = 0.19µg/ml) 100 times more potently than traditional kava in A549 cells in an in vitro luciferase-based assay. It is also reported to suppress the elevation of IKKα, p65, and COX-2 and the degradation of IκBα in A549 cultures stimulated with TNF-alpha; through Western Blot analysis.
Specifications

Specifications

99% by HPLC
5mg
274.3g/mol
White solid
C15H14O5
DMSO
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