MilliporeSigma Calbiochem NF-κB Activation Inhibitor X, Methysticin
Methysticin has been identified from kava to have potent NF-κB inhibitory activity and minimum toxicity
Manufacturer: MilliporeSigma 4804585MG
DescriptionMethysticin has been identified from kava to have potent NF-κB inhibitory activity and minimum toxicity. It is shown to inhibit NF-κB (IC50 = 0.19µg/ml) 100 times more potently than traditional kava in A549 cells in an in vitro luciferase-based assay. It is also reported to suppress the elevation of IKKα, p65, and COX-2 and the degradation of IκBα in A549 cultures stimulated with TNF-alpha; through Western Blot analysis.
|99% by HPLC|
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