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EMD Millipore Calbiochem™ Phenylmethylsulfonyl Fluoride Available on GSA/VA Contract for Federal Government customers only.

Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine residues.

Manufacturer:  EMD Millipore 5233225GM

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Catalog No. 52-332-25GM

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Irreversible inhibitor of serine proteases. Its mechanism of action is analogous to that of diisopropylfluorophosphate. PMSF causes sulfonylation of the active-site serine residues. Also reported to inhibit internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor, see AEBSF (Cat. No. 101500).
Description & Specifications


99% by GC
Protect from Moisture
serine proteases
EtOH, isopropanol, or MeOH
White to off-white crystalline solid
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