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MilliporeSigma™ Calbiochem™ Ru360

A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM).

Supplier:  MilliporeSigma™ 5574401SET

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Catalog No. 55-744-01SET


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Description

Description

A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM). Specifically blocks Ca2+ uptake into mitochondria in vitro (IC50 = 184 pM) and in situ in intact myocytes (complete block after incubation with ∽10μM of Ru360 for 30 min). Does not affect other cellular Ca2+ transport processes involved in cardiac muscle contraction, even at micromolar levels.
Specifications

Specifications

Reddish Brown
Ca2+ uptake into mitochondria in vitro
550.8g/mol
Hygroscopic, Protect from light
1 Set
97% by capillary electrophoresis
C2H26Cl3N8O5Ru2
deoxygenated H2O
Solid
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