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MilliporeSigma™ Calbiochem™ Ru360
A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM).
Supplier: MilliporeSigma™ 5574401SET
Description
A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM). Specifically blocks Ca2+ uptake into mitochondria in vitro (IC50 = 184 pM) and in situ in intact myocytes (complete block after incubation with ∽10μM of Ru360 for 30 min). Does not affect other cellular Ca2+ transport processes involved in cardiac muscle contraction, even at micromolar levels.Specifications
Reddish Brown | |
Ca2+ uptake into mitochondria in vitro | |
550.8g/mol | |
Hygroscopic, Protect from light | |
1 Set |
97% by capillary electrophoresis | |
C2H26Cl3N8O5Ru2 | |
deoxygenated H2O | |
Solid |
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