Calcium Channel beta-4 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA112671

Catalog No. 01-674-825

Description

A suggested positive control for this product is rat brain lysate.

This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy and juvenile myoclonic epilepsy. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Calcium Channel beta-4
• Classification: Polyclonal
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: O00305
• Gene Symbols: Cacnb4
• Immunogen: Synthetic peptide, conjugated to KLH, corresponding to the rat calcium channel beta4 subunit.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: Cacnb4
• Gene Alias: 3110038O15Rik; CAB4; Cacnb4; CACNLB4; calcium channel beta 4 subunit; calcium channel voltage-dependent subunit beta 4; calcium channel, voltage-dependent, beta 4 subunit; calcium voltage-gated channel auxiliary subunit beta 4; Cchb4; dihydropyridine-sensitive L-type, calcium channel beta-4 subunit; EA5; EIG9; EJM; EJM4; EJM6; lh; OTTHUMP00000207247; OTTHUMP00000207249; Voltage-dependent L-type calcium channel subunit beta-4
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 785
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov