Caldesmon/CALD1 Mouse anti-Human, Biotin, Clone: CALD1/820 + h-CALD, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP247819B
DescriptionCaldesmon/CALD1 Monoclonal antibody specifically detects Caldesmon/CALD1 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence.
|CALD1/820 + h-CALD|
|Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence|
|Recombinant full-length human CALD1 protein (CALD1/820); Crude human uterus extract (h-CALD)|
|Protein A or G purified|
|Cytoskeleton Markers, Phospho Specific|
|Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin)|
|PBS with 0.05% Sodium Azide|
|CAD, caldesmon, caldesmon 1, CDMH-CAD, HCAD, LCAD, L-CAD, MGC21352, NAG22|
|Store at 4C in the dark.|
|Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.|
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