Caldesmon/CALD1 Antibody (CALD1/1424R), Alexa Fluor™ 750, Novus Biologicals™

Rabbit Monoclonal Antibody

Supplier:  Novus Biologicals NBP254311AF750

Catalog No. NP24311A70

Description

Caldesmon/CALD1 Monoclonal specifically detects Caldesmon/CALD1 in Human, Rat samples. It is validated for Western Blot.

Specifications

• Antigen: Caldesmon/CALD1
• Classification: Monoclonal
• Conjugate: Alexa Fluor 750
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: CALD1
• Immunogen: Recombinant human full-length Caldesmon/CALD1 protein (Uniprot: Q05682 )
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120 150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70 80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This monoclonal antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
• Content And Storage: Store at 4°C in the dark.

• Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: CALD1/1424R
• Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
• Gene Alias: CAD, caldesmon, caldesmon 1, CDMH-CAD, HCAD, LCAD, L-CAD, MGC21352, NAG22
• Host Species: Rabbit
• Quantity: 0.1 mL
• Gene ID (Entrez): 800
• Target Species: Human, Rat
• Isotype: IgG