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Calpain 6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
$496.07
Specifications
Antigen | Calpain 6 |
---|---|
Concentration | 0.16 mg/mL |
Applications | Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-172-6038
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Proteintech Group Inc
101201AP150UL |
150 μL |
Each of 1 for $496.07
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Description
Calpain-6, also known as calpamodulin or calpain-X, is an intracellular, calcium-dependent cysteine protease. Calpain-6 has a much more tissue-specific expression in adults than the ubiquitous calpain-1 and calpain-2, and has thus far been found primarily in the placenta, although it is expressed embryonically in a number of tissues. The classical calpain family members consist of a common small subunit (calpain-4), and a large variable subunit, but it is not known if calpain-6 associates with a small subunit. Domains in the large subunit include the amino terminal domain-I, the proteinase domain-II, domain-III, and the EF-hand domain-IV (domain T in calpains 5 and 6). Located on the X chromosome, the calpain-6 sequence lacks the EF hand calcium-binding motif found in domain-IV of the classical calpains. In addition, the canonical active site Cys, His and Asn are modified to Lys, His, Asn in human and Lys, Tyr, Asn in mouse calpain-6, making it unlikely that calpain-6 is proteolytically active.Specifications
Calpain 6 | |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
O35646, O88501, Q9Y6Q1 | |
12338, 827, 83685 | |
Calpain 6 Fusion Protein Ag0160 | |
Primary | |
-20°C | |
CAPN6 |
0.16 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
calpain 6, Calpain like protease X linked, Calpamodulin, CalpM, CANPX, CAPN6, CAPNX | |
CAPN6 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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