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Calponin 1 Rabbit anti-Human, Mouse, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  Invitrogen MA527892

Catalog No. PIMA527892


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Description

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using Recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and maligt breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
Specifications

Specifications

Calponin 1
Recombinant Monoclonal
Unconjugated
CNN1
Liquid
Rabbit
IgG
100 μl
-20°C
Primary
1264, 12797
Immunocytochemistry, Immunofluorescence, Western Blot
RM262
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
P51911
Cnn1
A peptide corresponding to the C-terminus of human Calponin-1
Protein A
RUO
Antibody
Monoclonal
Human, Mouse
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