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Calsequestrin 2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 184221AP

Catalog No. 50-173-2150


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Description

Description

Calsequestrin (CASQ) is a Ca2+-binding protein present primarily in junctional sarcoplasmic reticulum of skeletal and cardiac muscle; the cardiac form (CASQ2) is encoded by a separate gene. The primary role of CASQ2 is buffering of the sarcoplasmic reticulum Ca2+ ions, but another role for CASQ2 has emerged recently: CASQ2 regulates the open probability of ryanodine receptor 2 (RyR2). Mutations in CASQ2 cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
Specifications

Specifications

Calsequestrin 2
0.26 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O09161, O14958, P51868
Calsequestrin 2, CASQ2, PDIB2
Rabbit
IgG
150 μL
-20°C
Primary
12373, 29209, 845
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
CASQ2
Liquid
CASQ2
Calsequestrin 2 Fusion Protein Ag13246
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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