CaMKII beta Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA141150

Catalog No. 01-675-727

Description

CAMK2B (CaMKII beta) is a serine/threonine kinase that plays a role in synaptic plasticity, synaptic vesicle mobilization and regulation of gene expression. As a dominant kinase in the central nervous system it may function in long term potentiation and neurotransmitter release. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.

Specifications

• Antigen: CaMKII beta
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAMK2B
• Gene Alias: Ca++/calmodulin-dependent protein kinase II beta subunit; calcium/calmodulin dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II subunit beta; CaM kinase II beta subunit; caM kinase II subunit beta; CAM2; CaMK II; CAMK2; CAMK2B; Camk2d; CAMKB; caMK-II subunit beta; caM-kinase II beta chain; Ck2b; hypothetical protein LOC525416; MGC29528; proline rich calmodulin-dependent protein kinase; β CaMKII; βCaMKII
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: Conc. Not Determined
• Formulation: whole serum with 50% glycerol and 0.025% sodium azide
• Gene Accession No.: P08413, P28652, Q13554
• Gene Symbols: CAMK2B
• Immunogen: Synthetic peptide corresponding to residues V(499) R R G S G T P E A E A P R Q(513) of human CaMKIIb.
• Regulatory Status: RUO
• Gene ID (Entrez): 12323, 24245, 816
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov