Carbonic Anhydrase VA Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA589996

Catalog No. PIPA589996

Description

Immunogen sequence: CAWQTSNNTL HPLWTVPVSV PGGTRQSPIN IQWRDSVYDP QLKPLRVSYE AASCLYIWNT GYLFQVEFDD ATEASGISGG PLENHYRLKQ FHFHWGAVNE GGSEHTVDGH AYPAELHLVH WNSVKYQNYK EAVVGENGLA VIGVFLKLGA HHQTLQRLVD ILPEIKHKDA RAAMRPFDPS TLLPTCWDYW TYAGSLTTPP LTESVTWIIQ KEPVEVAPSQ LSAFRTLLFS ALGEEEKMMV NNYRPLQPLM NRKVWASFQA TNEGTRS; Positive Samples: K-562, LO2, HepG2; Cellular Location: Mitochondrion

Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric juice. They show extensive diversity in distribution and in their subcellular localization. The human CA5A gene encodes for the CA V protein which is expressed in the mitochondrial matrix in liver tissues, but can also be detected in many other tissues. In ureagenesis, the CA V protein may be involved in providing bicarbonate to carbamoyl phosphate synthetase.

Specifications

• Antigen: Carbonic Anhydrase VA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Car5a
• Gene Alias: CA Y, CA5, CA5A, CA5AD, Car5, Car5a, Carbonate dehydratase VA, carbonic anhydrase 5 mitochondrial, carbonic anhydrase 5, mitochondrial, carbonic anhydrase 5A, carbonic anhydrase 5a, mitochondrial, carbonic anhydrase 5b, mitochondrial, carbonic anhydrase V, mitochondrial, carbonic anhydrase VA, carbonic anhydrase VA, mitochondrial, carbonic dehydratase, CAV, CAVA, CA-VA, GS1-21A4.1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12352
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 2.05 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
• Gene Accession No.: P23589
• Gene Symbols: Car5a
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 39-305 of human CA5A (NP_0017301)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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