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Carboxypeptidase A1 Mouse anti-Human, Clone: OTI2A3, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA524887

Catalog No. PIMA524887


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Description

Description

CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
Specifications

Specifications

Carboxypeptidase A1
Monoclonal
0.32 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P15085
Carboxypeptidase A1; CPA; CPA1
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
1357
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
OTI2A3
Unconjugated
CPA1
Liquid
CPA1
Recombit protein expressed in E.coli corresponding to amino acids 1-419 of CPA-1.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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