Carboxypeptidase A1 Mouse anti-Human, Clone: OTI2A3, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524887
DescriptionCPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Carboxypeptidase A1; CPA; CPA1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Recombit protein expressed in E.coli corresponding to amino acids 1-419 of CPA-1.|
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