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CARD8 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$395.30

Specifications

Antigen CARD8
Concentration 0.19 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-172-9506
SDP
Encompass_Preferred
View Documents
Proteintech Group Inc
145161AP150UL
150 μL
Each of 1 for $395.30
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Description

Description

Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD8. This protein interacts with DRAL, a p53-responsive protein implicated in the induction of apoptosis, and caspase-1 and its related proteins ICEBERG and pesudo-ICE. Although there are conflicting reports on whether CARD8 acts a pro- or anti-apoptotic protein, it has been suggested that it functions as an adaptor molecule regulating caspase-1 and NF-kappa-B activation.
Specifications

Specifications

CARD8
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human
IgG
-20°C
0.19 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications
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