Cdc42 GTPase inhibitor
Manufacturer: Tocris 5050/10
DescriptionCdc42 GTPase inhibitor (IC50 = 2µM). Reduces active levels of Cdc42 in aged hematopoietic stem cells (HSCs) to that in young HSCs. Reverses the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo. Increases histone H4K16 acetylation in aged HSCs.
- Chemical Name: 2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol
- Formula: C20H22N2O
- CAS Number: 425399-05-9
- Solubility: Soluble to 100mM in DMSO and to 50mM in ethanol
- Purity: >98