CASP7 Mouse anti-Human, Clone: 7-1-11, Abnova™
Mouse monoclonal antibody raised against human CASP7.
Manufacturer: Abnova Corporation MAB12590
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq]
|Mouse monoclonal antibody raised against human CASP7.|
|In PBS, 10mM Na3PO4, 50mM NaCl, pH 7.2 (0.1mM PMSF)|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to full length human CASP7.|
|Protein G purification|
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