Thermo Scientific Lab Vision Caspase 6 (Mch 2) Ab-3, Mouse Monoclonal Antibody
Ensure accurate, reproducible results in western blotting and immunoprecipitation procedures with Thermo Scientific Caspase 6 (Mch 2) Ab-3, Mouse Monoclonal Antibody.
Manufacturer: Thermo Scientific MS1126P0
Ensure accurate, reproducible results in western blotting and immunoprecipitation procedures with Thermo Scientific Caspase 6 (Mch 2) Ab-3, Mouse Monoclonal Antibody.Caspases play a major role in the transduction of the apoptotic signal and execution of apoptosis in mammalian cells. Caspase 3 (CPP32) and Caspase 6 (Mch2) are the major active caspases in apoptotic cells, and are activated in response to distinct apoptosis-inducing stimuli in all cell lines analyzed. Both CPP32 and Mch2 are present in apoptotic cells as multiple active species. Caspase-6 cleaves nuclear mitotic apparatus protein (NuMA) and mediates the shrinkage and fragmentation of nuclei.
Host Species: Mouse
Clone: 6CSP03; same as 14.1.190
Species Reactivity: Human. Others not tested.
Epitope: Caspase 6 prodomain
Immunogen: Recombinant human caspase 6 prodomain
Molecular Weight: 34 kDa
Positive Control: Jurkat cells
Cellular Localization: Cytoplasmic
- Western Blotting
USA: RUO; Int'l: RUO
|Caspase 6 (Mch 2) Ab-3|
|Recombinant human caspase 6 prodomain|
|Immunoprecipitation, Western Blot|
|6CSP03; same as 14.1.190|
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