Learn More
Epredia™ Lab Vision™ Actin, Smooth Muscle, Ab-1 Mouse Monoclonal Antibody, 40μg/mL, BSA and azide
Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Epredia™ Caspase 8 (FLICE) Ab-3, Mouse Monoclonal Antibody.
Supplier: Epredia™ MS1143P
Description
Caspase 8 binds to the death effector domain (DED) of FADD through an analogous DED domain present in tandem in the proform of the caspase 8 protein. Recruitment of caspase 8 to the Fas receptor results in oligomerization of the caspase 8 protein, which in turn drives its autoactivation through “self-cleavage”. Activated caspase 8 then activates other downstream caspases including caspase 9, thereby commiting the cell to undergo apoptosis.Host Species: Mouse
Clone: 8CSP03; same as 4.1.20
Isotype: IgG1
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: Recombinant full-length human Caspase 8 protein
Molecular Weight: 55 kDa
Positive Control: Jurkat cells
Cellular Localization: Cytoplasmic
Recommended for:
- Western Blotting
- Immunoprecipitation (Denatured verified)
Note:
USA: RUO; Int'l: RUO
Specifications
Caspase 8 (FLICE) Ab-3 | |
Monoclonal | |
200μg/mL | |
Mouse | |
1 mL | |
Apoptosis | |
Human | |
IgG1 |
Immunoprecipitation, Western Blot | |
8CSP03; same as 4.1.20 | |
Unconjugated | |
Recombinant full length human Caspase 8 protein | |
RUO | |
Primary | |
Concentrated |
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.