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Thermo Scientific™ Lab Vision™ Caspase 8 (FLICE) Ab-3, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ Caspase 8 (FLICE) Ab-3, Mouse Monoclonal Antibody.

$289.50 - $1095.00

Specifications

Antigen Caspase 8 (FLICE) Ab-3
Clone 8CSP03; same as 4.1.20
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Conjugate Unconjugated
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Products 5
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
MS1143P
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Thermo Scientific™
MS1143P
200μg/mL 1mL
Each for $1,007.00
Add to cart
 
MS1143P0
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Thermo Scientific™
MS1143P0
200μg/mL 100μL
Each for $289.50
Add to cart
 
MS1143P1
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Thermo Scientific™
MS1143P1
200μg/mL 500μL
Each for $696.00
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MS1143P1ABX
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Thermo Scientific™
MS1143P1ABX
1mg/mL 100μL
Each for $760.00
Add to cart
 
MS1143PABX
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Thermo Scientific™
MS1143PABX
1mg/mL 200μL
Each for $1,095.00
Add to cart
 
Description

Description

Ensure accurate, reproducible results in western blotting and immunoprecipitation experiments with Thermo Scientific™ Caspase 8 (FLICE) Ab-3, Mouse Monoclonal Antibody.

 

Caspase 8 binds to the death effector domain (DED) of FADD through an analogous DED domain present in tandem in the proform of the caspase 8 protein. Recruitment of caspase 8 to the Fas receptor results in oligomerization of the caspase 8 protein, which in turn drives its autoactivation through “self-cleavage”. Activated caspase 8 then activates other downstream caspases including caspase 9, thereby commiting the cell to undergo apoptosis.

Host Species: Mouse

Clone: 8CSP03; same as 4.1.20

Isotype: IgG1

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Recombinant full-length human Caspase 8 protein

Molecular Weight: 55 kDa

Positive Control: Jurkat cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Western Blotting
  • Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Caspase 8 (FLICE) Ab-3
Immunoprecipitation, Western Blot
Unconjugated
Murine
Apoptosis
Recombinant full length human Caspase 8 protein
8CSP03; same as 4.1.20
Monoclonal
Concentrated
RUO
Primary
IgG1
SDS
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