Invitrogen™ Catalase Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529183

Catalog No. PIPA529183

Description

Recommended positive controls: CAT-transfected 293T, mouse kidney, rat kidney. Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (88%), Drosophila (80%), Dog (97%), Pig (96%), Chicken (91%), Bovine (96%), Guinea pig (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Catalase is a homotetrameric heme-containing enzyme present within the matrix of all peroxisomes. It carries out a dismutation reaction in which hydrogen peroxide is converted to water and oxygen. Human catalase has the last four amino acids (-KANL) at the extreme C-terminus for peroxisome targeting. The monomer of human catalase is 61.3 kDa in molecular size. Catalase has been implicated as an important factor in inflammation, mutagenesis, prevention of apoptosis, and stimulation of a wide spectrum of tumors. Loss of catalase leads to the human genetic disease, acatalasemia, or Takahara's disease.

Specifications

• Antigen: Catalase
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cat
• Gene Alias: 2210418N07; Cas1; Cas-1; CAT; Cat01; catalase; catalase 1; Catl; CS1; Cs-1; CTA1; HGNC:1516; hypothetical protein LOC531682; MGC138422; MGC138424
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12359, 24248, 847
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.47 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P04040, P04762, P24270
• Gene Symbols: Cat
• Immunogen: Recombinant fragment corresponding to a region within amino acids 15 and 292 of Human Catalase.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov