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Thermo Scientific™ Lab Vision™ β-Catenin Rabbit Monoclonal Antibody

Ensure accurate and reproducible results in immunohistochemistry applications with this antibody, part of a comprehensive antibody portfolio.

$335.50 - $1178.00

Specifications

Antigen Catenin, beta
Clone E247
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Conjugate Unconjugated
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Products 4
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
RM2101S0
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Thermo Scientific™
RM2101S0
100μL Each for $335.50
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RM2101S
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Thermo Scientific™
RM2101S
1mL Each for $1,178.00
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RM2101R7
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Thermo Scientific™
RM2101R7
7mL Each for $633.50
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RM2101RQ
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Thermo Scientific™
RM2101RQ
12mL Each for $811.50
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Description

Description

Ensure accurate and reproducible results in immunohistochemistry applications with Thermo Scientific™ Catenin, β, Rabbit Monoclonal Antibody, part of a comprehensive antibody portfolio. Studies show rabbit monoclonal antibodies are more sensitive and specific than other available markers.

The catenins (α, β and γ) are ubiquitously expressed cytoplasmic proteins associated with E-cadherin at cellular junctions. β-catenin also binds to N-cadherin and co-immunoprecipitates with APC. Cadherin/catenin complexes are linked to the cytoskeleton via a direct association between α-actinin and α-catenin. Increased tyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellular adhesion. Mutations in the catenin gene, CTNNB1, have been implicated in its accumulation and various forms of carcinomas.

Host Species: Rabbit

Clone: E247

Species Reactivity: Human. Others not known.

Immunogen: A synthetic peptide derived from near the N-terminus of human β-catenin

Molecular Weight: 92 kDa

Positive Control: Breast CA

Cellular Localization: Cell Membrane

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)

Specifications

Specifications

Catenin, beta
Immunohistochemistry (Paraffin)
Unconjugated
IVD
Primary
E247
Monoclonal
Rabbit
Cancer and Tumor Biology
A synthetic peptide derived from near the N-terminus of human beta-catenin
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