BioVision Inc Cathepsin K Inhibitor Screening Kit (Fluorometric): Cathepsin K (CTSK) Inhibitor Screening Kit: Rapid & Convenient Fluorometric Assay to Screen Cathepsin-K Inhibitors. Includes Inhibitor Control, FF-FMK. High-Throughput adaptable. 100 Assays.
Manufacturer: BioVision Inc K150100
Cathepsin K (CTSK, EC 126.96.36.199), a lysosomal cysteine protease, is involved in osteoclastic bone remodeling and resorption. In addition, it also degrades collagen, gelatin and elastin. Biovision’s Cathepsin K Inhibitor Screening Kit utilizes the ability of active Cathepsin K to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin K-specific inhibitor, the cleavage of this substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize potential inhibitors of Cathepsin K. BioVision charges an Ice pack and Insulated Container fee of $25.00 for each order.
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