CaV1.2 Mouse anti-Hamster, Human, Mouse, Rabbit, Rat, Clone: S57-46, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527717
DescriptionCACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by CACNA1C this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.4|
|P22002, Q01815, Q13936|
|CACH3, CACN4, CACNA 1D, CACNL1A2, voltage dependent L type calcium channel subunit alpha 1D, alpha-1 subunit voltage-dependent calcium channel, calcium channel voltage-dependent L type alpha 1C subunit1, voltage-gated calcium channel alpha subunit Cav1.2, calcium channel L type, alpha 1 polypeptide isoform 1 cardic muscle, calcium channel cardic dihydropyridine-sensitive alpha-1 subunit, voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit splice variant 10, DHPR alpha-1 subunit, Voltage-gated calcium channel subunit alpha Cav1.2, Calcium channel L type alpha-1 polypeptide isoform 1 cardiac muscle|
|100101555, 100754788, 12288, 24239, 775|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot|
|Fusion protein amino acids 1507-1733 (intracellular carboxyl terminus) of rabbit Cav1.2|
|Hamster, Human, Mouse, Rabbit, Rat|
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